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Obstet Gynecol Sci. 2016 Mar;59(2):148-51. doi: 10.5468/ogs.2016.59.2.148. Epub 2016 Mar 16.

Hypertriglyceridemia-induced acute pancreatitis in pregnancy causing maternal death.

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Department of Obstetrics and Gynecology, Gil Hospital, Gachon University Graduate School of Medicine, Incheon, Korea.


Acute pancreatitis in pregnancy is rare and occurs in approximately 3 in 10,000 pregnancies. It rarely complicates pregnancy, and can occur during any trimester, however over half (52%) of cases occur during the third trimester and during the post-partum period. Gallstones are the most common cause of acute pancreatitis. On the other hand, acute pancreatitis caused by hypertriglyceridemia due to increase of estrogen during the gestational period is very unusual, but complication carries a higher risk of morbidity and mortality for both the mother and the fetus. We experienced a case of pregnant woman who died of acute exacerbation of hypertriglyceridemia-induced acute pancreatitis at 23 weeks of gestation. We report on progress and management of this case along with literature reviews.


Acute pancreatitis; Hypertriglyceridemia; Maternal death; Pregnancy

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