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Mol Cell Probes. 2016 Jun;30(3):178-81. doi: 10.1016/j.mcp.2016.03.004. Epub 2016 Mar 16.

Rare disease relations through common genes and protein interactions.

Author information

1
Escuela Politecnica Superior, Universidad Autonoma de Madrid, Madrid 28049, Spain.
2
Computational Systems Biology Group, National Centre for Biotechnology (CNB-CSIC), Madrid 28049, Spain.
3
Computational Systems Biology Group, National Centre for Biotechnology (CNB-CSIC), Madrid 28049, Spain. Electronic address: monica.chagoyen@cnb.csic.es.

Abstract

ODCs (Orphan Disease Connections), available at http://csbg.cnb.csic.es/odcs, is a novel resource to explore potential molecular relations between rare diseases. These molecular relations have been established through the integration of disease susceptibility genes and human protein-protein interactions. The database currently contains 54,941 relations between 3032 diseases.

KEYWORDS:

Biomedical databases; Disease relations; Protein interactions; Rare diseases

PMID:
26995712
DOI:
10.1016/j.mcp.2016.03.004
[Indexed for MEDLINE]

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