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HNO. 2016 Apr;64(4):217-20. doi: 10.1007/s00106-016-0138-6.

Treatment in elderly patients with head and neck cancer : A challenging dilemma.

Author information

1
Department of Otolaryngology Head and Neck Surgery, Philipp University of Marburg, Baldingerstr., 35043, Marburg, Germany. teymoort@med.uni-marburg.de.
2
Coordinator of the International Head and Neck Scientific Group, Padua, Italy.
3
Department of Otorhinolaryngology Head and Neck Surgery, University of Groningen University Medical Center Groningen, Groningen, The Netherlands.

Abstract

Despite the increasing number of elderly patients requiring treatment for head and neck cancer, there is insufficient available evidence about the oncological results of treatment and its tolerability in such patients. Owing to comorbidities, elderly patients often need complex evaluation and pretreatment management, which often results in their exclusion from clinical trials. The question of which patients constitute the highest-risk groups regarding treatment-related morbidity and mortality, and who can tolerate and benefit from aggressive treatment, has not been adequately studied. Biologic rather than chronologic age should be a more important factor in treatment protocols. Age-specific prospective clinical studies are needed on the treatment of head and neck cancer in elderly patients.

KEYWORDS:

Comorbidity; Elderly; Head and neck cancer; Survival; Treatment

PMID:
26992385
DOI:
10.1007/s00106-016-0138-6
[Indexed for MEDLINE]

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