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Blood. 2016 Mar 17;127(11):1386. doi: 10.1182/blood-2016-01-694935.

An oxidase road to platelet adhesion.

Author information

1
YALE SCHOOL OF MEDICINE.

Abstract

Platelet adhesion to collagen via collagen receptors is an important part of thrombosis. In this issue of Blood, Matsuura et al identify collagen receptors as previously unrecognized targets of the extracellular enzyme lysyl oxidase (LOX), the level of which is increased in myeloproliferative neoplasms (MPNs) and other conditions associated with pathological thromboses.

PMID:
26989190
DOI:
10.1182/blood-2016-01-694935
[Indexed for MEDLINE]

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