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Dermatol Ther. 2016 Jul;29(4):233-5. doi: 10.1111/dth.12343. Epub 2016 Mar 14.

Platelet-rich plasma as a novel treatment for lichen planopillaris.

Author information

1
Department of Dermatovenereology, University Hospital Center Sestre milosrdnice, Zagreb, Croatia.
2
University of Rome ("G. Marconi"), Rome, Italy.
3
Clinical Unit for Laboratory Hematology and Coagulation, Clinical Institute of Chemistry, University Hospital Center Sestre milosrdnice, Zagreb, Croatia.
4
Department of Pathology, University Hospital Center Sestre milosrdnice, Zagreb, Croatia.

Abstract

Treatment of lichen planopillaris (LPP) remains a significant challenge due to the irreversible damage inflicted on hair follicles combined with the low efficacy of existing treatments. We hypothesized that growth factors released by the use of platelet-rich plasma (PRP) may arrest the development of LPP. To test our hypothesis, we treated an LPP patient that has failed previous treatments with a new PRP regimen. Following PRP treatment and six months follow-up, the patient experienced complete regression of itching and hair shedding. To the best of our knowledge, this is the first report of successful treatment of LPP with a PRP regimen.

KEYWORDS:

alopecia; cicatricial alopecia; lichen planopillaris; local therapy; platelet-rich plasma

PMID:
26988129
DOI:
10.1111/dth.12343
[Indexed for MEDLINE]

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