Format

Send to

Choose Destination
Transcription. 2016 Mar 14;7(2):50-6. doi: 10.1080/21541264.2016.1163451. Epub 2016 Mar 17.

A single flexible RNAPII-CTD integrates many different transcriptional programs.

Author information

1
a Centre for Molecular Medicine and Therapeutics, Child and Family Research Institute, Department of Medical Genetics, University of British Columbia , Vancouver , British Columbia , Canada.

Abstract

The RNAPII-CTD functions as a binding platform for coordinating the recruitment of transcription associated factors. Altering CTD function results in gene expression defects, although mounting evidence suggests that these effects likely vary among species and loci. Here we highlight emerging evidence of species- and loci-specific functions for the RNAPII-CTD.

KEYWORDS:

C-terminal domain; CTD modifications; RNAPII; gene-specific; species-specific; transcription

PMID:
26985717
PMCID:
PMC4853039
DOI:
10.1080/21541264.2016.1163451
[Indexed for MEDLINE]
Free PMC Article

Supplemental Content

Full text links

Icon for Taylor & Francis Icon for PubMed Central
Loading ...
Support Center