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J Asian Nat Prod Res. 2016 May;18(5):423-8. doi: 10.1080/10286020.2016.1145671. Epub 2016 Mar 16.

Two new compounds from the fruits of Arctium lappa.

Author information

1
a Department of Pharmacy , China-Japan Friendship Hospital , Beijing 100029 , China.
2
b State Key Laboratory of Bioactive Substances and Functions of Natural Medicines , Institute of Materia Medica, Chinese Academy of Medical Sciences and Peking Union Medical College , Beijing 100050 , China.

Abstract

Phytochemical investigation of the extract of Arctii Fructus led to the isolation and characterization of two new compounds, named arctiisesquineolignan B (1) and arctiiphenolglycoside A (2). Their structures were elucidated by means of spectroscopic methods (UV, IR, HR-ESI-MS, 1D and 2D NMR) and chemical evidence, as well as by comparison with known analogs in the literature. Compound 2 exhibited stronger antioxidant activity than the positive control ascorbic acid at a concentration of 10 μM.

KEYWORDS:

Arctii Fructus; Arctium lappa; antioxidant activity; phenolic diglycoside; sesquineolignan

PMID:
26981771
DOI:
10.1080/10286020.2016.1145671
[Indexed for MEDLINE]

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