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Nutrients. 2016 Mar 10;8(3):156. doi: 10.3390/nu8030156.

Dietary Natural Products for Prevention and Treatment of Liver Cancer.

Author information

  • 1Guangdong Provincial Key Laboratory of Food, Nutrition and Health, School of Public Health, Sun Yat-Sen University, Guangzhou 510080, China. zhouyuesysu@163.com.
  • 2Guangdong Provincial Key Laboratory of Food, Nutrition and Health, School of Public Health, Sun Yat-Sen University, Guangzhou 510080, China. saferide@126.com.
  • 3Guangdong Provincial Key Laboratory of Food, Nutrition and Health, School of Public Health, Sun Yat-Sen University, Guangzhou 510080, China. zwky740359@163.com.
  • 4Guangdong Provincial Key Laboratory of Food, Nutrition and Health, School of Public Health, Sun Yat-Sen University, Guangzhou 510080, China. zhengj37@mail2.sysu.edu.cn.
  • 5School of Chinese Medicine, The University of Hong Kong, Hong Kong, China. lishasl0308@163.com.
  • 6Guangdong Provincial Key Laboratory of Food, Nutrition and Health, School of Public Health, Sun Yat-Sen University, Guangzhou 510080, China. lihuabin@mail.sysu.edu.cn.
  • 7South China Sea Bioresource Exploitation and Utilization Collaborative Innovation Center, Sun Yat-Sen University, Guangzhou 510006, China. lihuabin@mail.sysu.edu.cn.

Abstract

Liver cancer is the most common malignancy of the digestive system with high death rate. Accumulating evidences suggests that many dietary natural products are potential sources for prevention and treatment of liver cancer, such as grapes, black currant, plum, pomegranate, cruciferous vegetables, French beans, tomatoes, asparagus, garlic, turmeric, ginger, soy, rice bran, and some edible macro-fungi. These dietary natural products and their active components could affect the development and progression of liver cancer in various ways, such as inhibiting tumor cell growth and metastasis, protecting against liver carcinogens, immunomodulating and enhancing effects of chemotherapeutic drugs. This review summarizes the potential prevention and treatment activities of dietary natural products and their major bioactive constituents on liver cancer, and discusses possible mechanisms of action.

KEYWORDS:

anticancer; fruit; liver cancer; spice; vegetable

PMID:
26978396
PMCID:
PMC4808884
DOI:
10.3390/nu8030156
[PubMed - indexed for MEDLINE]
Free PMC Article
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