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Int J Surg Case Rep. 2016;21:125-8. doi: 10.1016/j.ijscr.2016.03.004. Epub 2016 Mar 10.

A rare case of true carcinosarcoma of the breast.

Author information

1
Department of Gastroenterology, Endocrinology and Surgery, Breast Unit, AOU "Federico II", Via S.Pansini 5, 80131 Naples, Italy.
2
Department of Biomorphological and Functional Sciences, Section of Pathologic Anatomy, Faculty of Medicine and Surgery, University of Naples "Federico II", Via S. Pansini 5, 80131 Naples, Italy.
3
Department of Clinical Medicine and Surgery, Faculty of Medicine and Surgery, University of Naples "Federico II", Via S. Pansini 5, 80131 Naples, Italy.
4
Department of Senology, Asur Marche Area Vasta 1, Santa Maria della Misericordia, Via Comandino 70, Urbino, Italy.
5
Breast Surgery Unit, IRCCS-Arcispedale Santa Maria Nuova, Viale Risorgimento 80, 42123 Reggio Emilia, Italy.
6
Department of Clinical Medicine and Surgery, Faculty of Medicine and Surgery, University of Naples "Federico II", Via S. Pansini 5, 80131 Naples, Italy. Electronic address: nicolarocco2003@gmail.com.

Abstract

BACKGROUND:

True carcinosarcoma of the breast is an extremely rare condition, accounting for 0.08-0.2% of all breast malignancies. The correct definition of this tumor requires both a carcinomatous component and a malignant non-epithelial component of mesenchymal origin, without evidence of a transition zone between the two elements.

CASE PRESENTATION:

We present a case of a 49-year-old woman presenting with a 4cm mass at the level of her left breast upper-outer quadrant with a histologic diagnosis of true carcinosarcoma of the breast.

DISCUSSION:

The most appropriate therapeutic regimens for breast carcinosarcoma are still unclear because of the rarity of this condition, but Breast Conserving Treatment (BCT) followed by adjuvant chemotherapy seems to provide a prognosis equalling that of usual Invasive Ductal Carcinoma of the breast.

KEYWORDS:

Biphasic metaplastic sarcomatoid carcinoma; Carcinosarcoma; Rare breast tumours

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