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Biomed Opt Express. 2016 Jan 6;7(2):287-301. doi: 10.1364/BOE.7.000287. eCollection 2016 Feb 1.

Total retinal blood flow measurement by three beam Doppler optical coherence tomography.

Author information

1
Center for Medical Physics and Biomedical Engineering, Medical University of Vienna, Austria; richard.haindl@meduniwien.ac.at.
2
Center for Medical Physics and Biomedical Engineering, Medical University of Vienna, Austria; Harvard Medical School and Wellman Center for Photomedicine, Massachusetts General Hospital, Boston, USA.
3
Center for Medical Physics and Biomedical Engineering, Medical University of Vienna, Austria.
4
Center for Medical Physics and Biomedical Engineering, Medical University of Vienna, Austria; christoph.hitzenberger@meduniwien.ac.at.

Abstract

We present measurements of total retinal blood flow in healthy volunteers using a three beam Doppler optical coherence tomography (D-OCT) technique. This technology has the advantage of a precise determination of the flow vector without the use of any a-priori information on the vessel geometry. Circular D-OCT scans around the optic disc were recorded and venous as well as arterial total blood flow was determined and compared for each subject. The reproducibility of the method was assessed in 6 subjects by repeated measurements. Only small deviations of around 6% between the measurements were found which indicates the high precision of the proposed method.

KEYWORDS:

(110.4500) Optical coherence tomography; (170.0110) Imaging systems; (170.0170) Medical optics and biotechnology; (170.2655) Functional monitoring and imaging; (170.3340) Laser Doppler velocimetry

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