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World J Gastroenterol. 2016 Mar 7;22(9):2828-36. doi: 10.3748/wjg.v22.i9.2828.

Early complications after interventions in patients with acute pancreatitis.

Author information

1
Ai-Lin Wei, Qiang Guo, Ming-Jun Wang, Wei-Ming Hu, Zhao-Da Zhang, Department of Pancreatic Surgery, West China Hospital, Chengdu 610041, Sichuan Province, China.

Abstract

AIM:

To identify the possible predictors of early complications after the initial intervention in acute necrotizing pancreatitis.

METHODS:

We collected the medical records of 334 patients with acute necrotizing pancreatitis who received initial intervention in our center. Complications associated with predictors were analyzed.

RESULTS:

The postoperative mortality rate was 16% (53/334). Up to 31% of patients were successfully treated with percutaneous catheter drainage alone. The rates of intra-abdominal bleeding, colonic fistula, and progressive infection were 15% (50/334), 20% (68/334), and 26% (87/334), respectively. Multivariate analysis indicated that Marshall score upon admission, multiple organ failure, preoperative respiratory infection, and sepsis were the predictors of postoperative progressive infection (P < 0.05). Single organ failure, systemic inflammatory response syndrome upon admission, and C-reactive protein level upon admission were the risk factors of postoperative colonic fistula (P < 0.05). Moreover, preoperative Marshall score, organ failure, sepsis, and preoperative systemic inflammatory response syndrome were the risk factors of postoperative intra-abdominal bleeding (P < 0.05).

CONCLUSION:

Marshall score, organ failures, preoperative respiratory infection, sepsis, preoperative systemic inflammatory response syndrome, and C-reactive protein level upon admission are associated with postoperative complications.

KEYWORDS:

Acute necrotizing pancreatitis; Colonic fistula; Intervention complications; Intra-abdominal bleeding; Progressive infection

PMID:
26973421
PMCID:
PMC4778005
DOI:
10.3748/wjg.v22.i9.2828
[Indexed for MEDLINE]
Free PMC Article

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