Intracerebral hemorrhage with intraventricular extension and no hydrocephalus may not increase mortality or severe disability

J Clin Neurosci. 2016 Aug:30:56-59. doi: 10.1016/j.jocn.2015.11.028. Epub 2016 Mar 10.

Abstract

This paper aimed to test the hypothesis that intraventricular extension of spontaneous intracerebral hemorrhage (ICH) in the absence of hydrocephalus is not associated with increased mortality or severe disability. We performed a retrospective consecutive cohort study of patients with primary spontaneous ICH who were admitted to a single institution. Multivariate logistic regression analysis was used to assess the association of each variable with functional outcome as measured by the modified Rankin Scale (mRS). A total of 164 patients met our inclusion criteria and were included in the study. Only hydrocephalus (p=0.002) and hematoma volume (p=0.006) were significantly associated with mortality or poor functional outcome (mRS of 3 to 6). In contrast, the presence of intraventricular hematoma was not independently associated with poor functional outcome. The presence of intraventricular extension of ICH in the absence of hydrocephalus may not increase mortality or disability.

Keywords: Hydrocephalus; Intracerebral hemorrhage; Intraventricular hemorrhage; Outcome; Prognosis.

MeSH terms

  • Adult
  • Aged
  • Aged, 80 and over
  • Cerebral Hemorrhage / complications
  • Cerebral Hemorrhage / mortality*
  • Cerebral Hemorrhage / pathology*
  • Cohort Studies
  • Female
  • Hematoma / complications
  • Hematoma / mortality
  • Hematoma / pathology
  • Humans
  • Hydrocephalus
  • Male
  • Middle Aged
  • Prognosis
  • Retrospective Studies