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Chromosoma. 2016 Jun;125(3):355-60. doi: 10.1007/s00412-016-0583-8. Epub 2016 Mar 12.

Evolutionary history of the mammalian synaptonemal complex.

Author information

1
Department of Cell and Developmental Biology, Biocenter, University of Würzburg, 97074, Würzburg, Germany.
2
Université Lyon 1, CNRS, UMR5558, Laboratoire de Biométrie et Biologie Evolutive, 43 bd du 11 novembre 1918, Villeurbanne, 69622, France.
3
Institut de Génomique Fonctionnelle de Lyon, École Normale Supérieure de Lyon, CNRS, Université Lyon 1, Lyon, France.
4
Department of Cell and Developmental Biology, Biocenter, University of Würzburg, 97074, Würzburg, Germany. benavente@biozentrum.uni-wuerzburg.de.

Abstract

The synaptonemal complex (SC), a key structure of meiosis that assembles during prophase I, has been initially described 60 years ago. Since then, the structure has been described in many sexually reproducing organisms. However, the SC protein components were characterized in only few model organisms. Surprisingly, they lacked an apparent evolutionary relationship despite the conserved structural organization of the SC. For better understanding of this obvious discrepancy, the evolutionary history of the SC and its individual components has been investigated in Metazoa in detail. The results are consistent with the notion of a single origin of the metazoan SC and provide evidence for a dynamic evolutionary history of the SC components. In this mini review, we recapitulate and discuss new insights into metazoan SC evolution.

KEYWORDS:

Evolution; Mammals; Meiosis; Metazoans; Phylogeny; Synaptonemal complex

PMID:
26968413
DOI:
10.1007/s00412-016-0583-8
[Indexed for MEDLINE]

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