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Mol Biosyst. 2016 May 24;12(6):1731-45. doi: 10.1039/c6mb00023a.

Peptide-tags for site-specific protein labelling in vitro and in vivo.

Author information

1
Institut für Biochemie, Universität Leipzig, Brüderstrasse 34, D-04103 Leipzig, Germany. abeck-sickinger@uni-leipzig.de.
2
Institut für Chemie, Humboldt-Universität zu Berlin, Brook-Taylor-Strasse 2, D-12489 Berlin, Germany. oliver.seitz@chemie.hu-berlin.de.

Abstract

Peptide-tag based labelling can be achieved by (i) enzymes (ii) recognition of metal ions or small molecules and (iii) peptide-peptide interactions and enables site-specific protein visualization to investigate protein localization and trafficking.

PMID:
26960991
DOI:
10.1039/c6mb00023a
[Indexed for MEDLINE]

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