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Rev Med Inst Mex Seguro Soc. 2016 Mar-Apr;54(2):211-24.

[Technical guidelines for the prevention, diagnosis and treatment of Zika virus infection].

[Article in Spanish; Abstract available in Spanish from the publisher]

Author information

Coordinación Técnica de Excelencia Clínica, Unidad de Atención Médica, Dirección de Prestaciones Médicas, Instituto Mexicano del Seguro Social, Ciudad de México, México.


in English, Spanish

Infection Zika virus is an emerging disease in the Americas region, which is caused by Zika virus (ZIKV), an arbovirus of the flavivirus genus. The ZIKV is transmitted by the bite of Aedes mosquitoes, both in urban and jungle area. After the mosquito bite, the disease symptoms usually appear after an incubation period of three to twelve days. The infection may be asymptomatic or presented with fever and not purulent conjunctivitis, headache, myalgia, arthralgia, asthenia, maculopapular rash, edema in lower limbs and, less frequently, retro-orbital pain, anorexia, vomiting, diarrhea or pain abdominal. Symptoms last for 4-7 days and are self-limiting. Neurological and autoimmune complications are rare. Since 2014 it has been detected native circulation of Zika virus in the Americas. So far, there is no specific antiviral treatment or effective vaccine, so it's giving priority symptomatic and supportive treatment for the acute phase and make an early diagnosis of atypical and severe forms.


Arbovirus infections; Arboviruses; Communicable disease control; Epidemiology; Virus diseases

[Indexed for MEDLINE]

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