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PLoS One. 2016 Mar 8;11(3):e0150982. doi: 10.1371/journal.pone.0150982. eCollection 2016.

A Human "eFP" Browser for Generating Gene Expression Anatograms.

Author information

1
Department of Cell & Systems Biology, 25 Willcocks Street, University of Toronto, Toronto, ON, M5S 3B2, Canada.
2
Centre for the Analysis of Genome Evolution and Function, 25 Willcocks Street, University of Toronto, Toronto, ON, M5S 3B2, Canada.
3
Department of Biological Sciences, 1265 Military Trail, University of Toronto Scarborough, Toronto, ON, M1C 1A4, Canada.

Abstract

Transcriptomic studies help to further our understanding of gene function. Human transcriptomic studies tend to focus on a particular subset of tissue types or a particular disease state; however, it is possible to collate into a compendium multiple studies that have been profiled using the same expression analysis platform to provide an overview of gene expression levels in many different tissues or under different conditions. In order to increase the knowledge and understanding we gain from such studies, intuitive visualization of gene expression data in such a compendium can be useful. The Human eFP ("electronic Fluorescent Pictograph") Browser presented here is a tool for intuitive visualization of large human gene expression data sets on pictographic representations of the human body as gene expression "anatograms". Pictographic representations for new data sets may be generated easily. The Human eFP Browser can also serve as a portal to other gene-specific information through link-outs to various online resources.

PMID:
26954504
PMCID:
PMC4783024
DOI:
10.1371/journal.pone.0150982
[Indexed for MEDLINE]
Free PMC Article

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