Format

Send to

Choose Destination
J Neurosci Methods. 2016 May 1;264:47-56. doi: 10.1016/j.jneumeth.2016.03.001. Epub 2016 Mar 2.

The first step for neuroimaging data analysis: DICOM to NIfTI conversion.

Author information

1
Center for Cognitive and Behavioral Brain Imaging, The Ohio State University, Columbus, OH 43210, USA.
2
Medical Physics & Clinical Engineering, Nottingham University Hospitals, Nottingham, UK.
3
Wellcome Trust Centre for Neuroimaging, University College London, London, UK.
4
Lewis Center for Neuroimaging, University of Oregon, Eugene, OR 97403, USA.
5
McCausland Center for Brain Imaging, University of South Carolina, Columbia, SC 29208, USA. Electronic address: rorden@sc.edu.

Abstract

BACKGROUND:

Clinical imaging data are typically stored and transferred in the DICOM format, whereas the NIfTI format has been widely adopted by scientists in the neuroimaging community. Therefore, a vital initial step in processing the data is to convert images from the complicated DICOM format to the much simpler NIfTI format. While there are a number of tools that usually handle DICOM to NIfTI conversion seamlessly, some variations can disrupt this process.

NEW METHOD:

We provide some insight into the challenges faced with image conversion. First, different manufacturers implement the DICOM format differently which complicates the conversion. Second, different modalities and sub-modalities may need special treatment during conversion. Lastly, the image transferring and archiving can also impact the DICOM conversion.

RESULTS:

We present results in several error-prone domains, including the slice order for functional imaging, phase encoding direction for distortion correction, effect of diffusion gradient direction, and effect of gantry correction for some imaging modality.

COMPARISON WITH EXISTING METHODS:

Conversion tools are often designed for a specific manufacturer or modality. The tools and insight we present here are aimed at different manufacturers or modalities.

CONCLUSIONS:

The imaging conversion is complicated by the variation of images. An understanding of the conversion basics can be helpful for identifying the source of the error. Here we provide users with simple methods for detecting and correcting problems. This also serves as an overview for developers who wish to either develop their own tools or adapt the open source tools created by the authors.

KEYWORDS:

DICOM; NIfTI; Neuroimaging

PMID:
26945974
DOI:
10.1016/j.jneumeth.2016.03.001
[Indexed for MEDLINE]

Supplemental Content

Full text links

Icon for Elsevier Science
Loading ...
Support Center