Format

Send to

Choose Destination
See comment in PubMed Commons below
Environ Res. 2016 May;147:365-72. doi: 10.1016/j.envres.2016.02.034. Epub 2016 Mar 3.

Using silicone wristbands to evaluate preschool children's exposure to flame retardants.

Author information

  • 1College of Public Health and Human Sciences, Oregon State University, Corvallis, OR 97331, United States.
  • 2Department of Environmental and Molecular Toxicology, Corvallis, OR 97331, United States.
  • 3College of Public Health and Human Sciences, Oregon State University, Corvallis, OR 97331, United States; Oregon State University Cascades Campus, Bend, OR 97701, United States.
  • 4Department of Environmental and Molecular Toxicology, Corvallis, OR 97331, United States. Electronic address: kim.anderson@oregonstate.edu.

Abstract

Silicone wristbands can be used as passive sampling tools for measuring personal environmental exposure to organic compounds. Due to the lightweight and simple design, the wristband may be a useful technique for measuring children's exposure. In this study, we tested the stability of flame retardant compounds in silicone wristbands and developed an analytical approach for measuring 41 flame retardants in the silicone wristband in order to evaluate exposure to these compounds in preschool-aged children. To evaluate the robustness of using wristbands to measure flame retardants, we evaluated the stability of 3 polybrominated diphenyl ethers (BDEs), and 2 organophosphate flame retardants (OPFRs) in wristbands over 84 days and did not find any evidence of significant loss over time at either 4 or -20°C (p>0.16). We recruited a cohort of 92 preschool aged children in Oregon to wear the wristband for 7 days in order to characterize children's acceptance of the technology, and to characterize their exposure to flame retardants. Seventy-seven parents returned the wristbands for analysis of 35 BDEs, 4 OPFRs, and 2 other brominated flame retardants although 5 were excluded from the exposure assessment due to protocol deviations (n=72). A total of 20 compounds were detected above the limit of quantitation, and 11 compounds including 4 OPFRs and 7 BDEs were detected in over 60% of the samples. Children's gender, age, race, recruitment site, and family context were not significantly associated with returning wristbands or compliance with protocols. Comparisons between flame retardant data and socio-demographic information revealed significant differences in total exposures to both ΣBDEs and ΣOPFRs based on age of house, vacuuming frequency, and family context. These results demonstrate that preschool children in Oregon are exposed to BDEs that are no longer being produced in the United States and to OPFRs that have been used as an alternative to polybrominated compounds. Silicone wristbands were well tolerated by young children and were useful for characterizing personal exposure to flame retardants that were not bound to particulate matter.

KEYWORDS:

BDEs; Exposure assessment; OPFRs; Personal monitoring; triphenyl phosphate

PMID:
26945619
PMCID:
PMC4821754
[Available on 2017-05-01]
DOI:
10.1016/j.envres.2016.02.034
[PubMed - indexed for MEDLINE]
PubMed Commons home

PubMed Commons

0 comments
How to join PubMed Commons

    Supplemental Content

    Full text links

    Icon for Elsevier Science
    Loading ...
    Support Center