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Dermatol Surg. 2016 Mar;42(3):392-402. doi: 10.1097/DSS.0000000000000640.

Nonablative Fractional Laser Resurfacing for Acne Scarring in Patients With Fitzpatrick Skin Phototypes IV-VI.

Author information

1
*Skin of Color Center, Department of Dermatology, Mount Sinai St. Luke's, New York, New York; †Summit Medical Group, Berkeley Heights, New Jersey; ‡Department of Dermatology, University of Texas Southwestern Medical Center, Dallas, Texas; §Department of Dermatology, Loma Linda University, Loma Linda, California; ‖Department of Dermatology, Tufts School of Medicine, Boston, Massachusetts; ¶Department of Dermatology, Northwestern University, Chicago, Illinois; #Department of Epidemiology, Rollins School of Public Health, Emory University, Atlanta, Georgia.

Abstract

BACKGROUND:

There is a paucity of studies investigating laser resurfacing in Fitzpatrick skin phototypes (SPT) IV to VI.

OBJECTIVE:

To assess the efficacy and safety of fractional nonablative laser resurfacing in the treatment of acne scarring in patients with SPT IV to VI.

METHODS AND MATERIALS:

The authors conducted a randomized, investigator-blinded and rater-blinded, split-face comparative study of adults with SPT IV to VI and facial acne scars treated with 2 different density settings and the same fluence.

RESULTS:

Quantitative global scarring grading system (QGSGS) scores were significantly improved from baseline at 16 and 24 weeks (p = .0277). Improvements in QGSGS scores after higher and lower density treatments were statistically similar (p = .96). The live-blinded dermatologist, the blinded dermatologist photoraters, and the patients rated scars as being significantly more improved by visual analog scale at weeks 16 and 24 compared with baseline (p < .001) for both treatment densities. Five of 7 and 3 of 7 patients in the higher and lower density group, respectively, experienced mild or moderate hyperpigmentation as an investigator observed site reaction.

CONCLUSION:

The nonablative 1550-nm fractional laser is safe and efficacious in treating acne scaring in Fitzpatrick skin types IV to VI. Self-limited postinflammatory hyperpigmentation was a common occurrence, especially with higher treatment densities.

PMID:
26945321
DOI:
10.1097/DSS.0000000000000640
[Indexed for MEDLINE]

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