Abstract
Granulex is an aerosolized spray (Dow B. Hickman Pharmaceuticals, Sugar Land, TX 77487) that contains trypsin, Peru balsam, and castor oil. It has been available for many years as a topical spray for the treatment of decubitus ulcers. We used Granulex to promote tissue healing of a necrotic ulcer of the oral mucosa in a patient with advanced oropharyngeal squamous cell carcinoma.
MeSH terms
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Adult
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Antineoplastic Combined Chemotherapy Protocols / therapeutic use*
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Balsams / administration & dosage
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Balsams / therapeutic use*
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Carcinoma, Squamous Cell / drug therapy
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Carcinoma, Squamous Cell / pathology
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Carcinoma, Squamous Cell / surgery*
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Castor Oil / administration & dosage
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Castor Oil / therapeutic use*
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Cisplatin / administration & dosage
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Cytarabine / administration & dosage
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Drug Combinations / administration & dosage
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Drug Combinations / therapeutic use
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Female
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Humans
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Hydroxyurea / administration & dosage
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Mouth Mucosa
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Mouth Neoplasms / drug therapy
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Mouth Neoplasms / pathology
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Mouth Neoplasms / surgery*
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Oral Hygiene
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Trypsin / administration & dosage
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Trypsin / therapeutic use*
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Wound Healing / drug effects*
Substances
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Balsams
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Drug Combinations
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Granulex
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Cytarabine
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Castor Oil
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Trypsin
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Cisplatin
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Hydroxyurea