Use of a trypsin, Peru balsam, and castor oil spray on the oral mucosa: case report and review of the literature

Pharmacotherapy. 1989;9(6):386-8. doi: 10.1002/j.1875-9114.1989.tb04154.x.

Abstract

Granulex is an aerosolized spray (Dow B. Hickman Pharmaceuticals, Sugar Land, TX 77487) that contains trypsin, Peru balsam, and castor oil. It has been available for many years as a topical spray for the treatment of decubitus ulcers. We used Granulex to promote tissue healing of a necrotic ulcer of the oral mucosa in a patient with advanced oropharyngeal squamous cell carcinoma.

Publication types

  • Case Reports
  • Review

MeSH terms

  • Adult
  • Antineoplastic Combined Chemotherapy Protocols / therapeutic use*
  • Balsams / administration & dosage
  • Balsams / therapeutic use*
  • Carcinoma, Squamous Cell / drug therapy
  • Carcinoma, Squamous Cell / pathology
  • Carcinoma, Squamous Cell / surgery*
  • Castor Oil / administration & dosage
  • Castor Oil / therapeutic use*
  • Cisplatin / administration & dosage
  • Cytarabine / administration & dosage
  • Drug Combinations / administration & dosage
  • Drug Combinations / therapeutic use
  • Female
  • Humans
  • Hydroxyurea / administration & dosage
  • Mouth Mucosa
  • Mouth Neoplasms / drug therapy
  • Mouth Neoplasms / pathology
  • Mouth Neoplasms / surgery*
  • Oral Hygiene
  • Trypsin / administration & dosage
  • Trypsin / therapeutic use*
  • Wound Healing / drug effects*

Substances

  • Balsams
  • Drug Combinations
  • Granulex
  • Cytarabine
  • Castor Oil
  • Trypsin
  • Cisplatin
  • Hydroxyurea