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J Int Soc Sports Nutr. 2016 Feb 29;13:7. doi: 10.1186/s12970-016-0119-x. eCollection 2016.

Effects of combined β-hydroxy-β-methylbutyrate (HMB) and whey protein ingestion on symptoms of eccentric exercise-induced muscle damage.

Author information

1
Department of Hygiene and Public Health, Nippon Sport Science University, 7-1-1 Fukasawa, Setagaya, Tokyo, Japan.
2
Laboratory of Health and Sports Sciences, Meiji Gakuin University, 1518 Kamikurata, Totsuka, Yokohama, Kanagawa Japan.
3
The Research Institute of Nippon Sport Science University, 7-1-1 Fukasawa, Setagaya, Tokyo, Japan.
4
Graduate School of Education, Okayama University, 3-1-1 Tsushimanaka, Kita, Okayama, Japan.
#
Contributed equally

Abstract

BACKGROUND:

The purpose of this study was to examine the effects of combined β-hydroxy-β-methylbutyrate (HMB) and whey protein ingestion on muscle strength and damage following a single bout of eccentric exercise.

METHODS:

Eighteen untrained male subjects were assigned to HMB and Whey protein (HMB + Whey; 3 g/day HMB and 36.6 g/day whey protein, n = 6), HMB (3 g/day, n = 6), or whey protein (36.6 g/day, n = 6) groups. Ingestion commenced 7 days before non-dominant elbow flexor eccentric exercise (30 deg/sec, 6 reps × 7 sets) and continued until 4 days post-exercise. The maximal isometric strength, muscle soreness, plasma creatine kinase (CK), lactate dehydrogenase (LDH) were assessed pre-exercise, and at 1, 2, 3, and 5 days after exercise.

RESULTS:

The change scores of maximal isometric strength significantly decreased at day 1, 2, and 5 in the whey protein group compared to pre value and that in HMB + Whey protein and HMB groups decreased at day 1 and 5. The muscle soreness significantly increased in the whey and HMB + Whey protein groups at day 3 compared to pre value (p < 0.05). CK and LDH significantly increased (time effect: p < 0.05) after exercise. However, all data were not significant difference among the groups.

CONCLUSIONS:

These results suggest that ingestion of combined HMB and whey protein does not have a role to inhibit muscle strength loss and soreness, and decrease in muscle damage markers after eccentric exercise in comparison with HMB and whey protein alone.

KEYWORDS:

Amino acids; Lengthening; Muscle soreness; Muscle strength

PMID:
26933398
PMCID:
PMC4772288
DOI:
10.1186/s12970-016-0119-x
[Indexed for MEDLINE]
Free PMC Article

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