Format

Send to

Choose Destination
Arch Emerg Med. 1989 Dec;6(4):251-6.

A comparative double blind study of amoxycillin/clavulanate vs placebo in the prevention of infection after animal bites.

Author information

1
Accident and Emergency Department, Middlesbrough General Hospital, England.

Abstract

The value of prophylactic antibiotics in the treatment of animal bites is uncertain. A prospective double blind stratified trial was performed comparing a broad spectrum antibiotic amoxycillin/clavulanate with placebo in full thickness animal bite wounds in a series of 185 consecutive patients. In wounds less than 9 h old, no significant benefit was found with the antibiotic. In older wounds, presenting 9-24 h after injury, the infection rate was reduced significantly (P = 0.023), although the numbers were small. We recommend the use of such an antibiotic on wounds 9-24 h old and query its use in more recent injuries, unless tendons or joints are likely to be involved.

PMID:
2692580
PMCID:
PMC1285624
DOI:
10.1136/emj.6.4.251
[Indexed for MEDLINE]
Free PMC Article

Supplemental Content

Full text links

Icon for PubMed Central
Loading ...
Support Center