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Magn Reson Med. 2017 Mar;77(3):979-988. doi: 10.1002/mrm.26173. Epub 2016 Feb 28.

MR fingerprinting using the quick echo splitting NMR imaging technique.

Author information

1
Dept. of Biomedical Engineering, Case Western Reserve University, Cleveland, Ohio, USA.
2
Dept. of Radiology, Case Western Reserve University, Cleveland, Ohio, USA.
3
Siemens AG, Healthcare Sector, Magnetic Resonance, Erlangen, Germany.

Abstract

PURPOSE:

The purpose of the study is to develop a quantitative method for the relaxation properties with a reduced radio frequency (RF) power deposition by combining magnetic resonance fingerprinting (MRF) technique with quick echo splitting NMR imaging technique (QUEST).

METHODS:

A QUEST-based MRF sequence was implemented to acquire high-order echoes by increasing the gaps between RF pulses. Bloch simulations were used to calculate a dictionary containing the range of physically plausible signal evolutions using a range of T1 and T2 values based on the pulse sequence. MRF-QUEST was evaluated by comparing to the results of spin-echo methods. The specific absorption rate (SAR) of MRF-QUEST was compared with the clinically available methods.

RESULTS:

MRF-QUEST quantifies the relaxation properties with good accuracy at the estimated head SAR of 0.03 W/kg. T1 and T2 values estimated by MRF-QUEST are in good agreement with the traditional methods.

CONCLUSIONS:

The combination of the MRF and the QUEST provides an accurate quantification of T1 and T2 simultaneously with reduced RF power deposition. The resulting lower SAR may provide a new acquisition strategy for MRF when RF energy deposition is problematic. Magn Reson Med 77:979-988, 2017. © 2016 International Society for Magnetic Resonance in Medicine.

KEYWORDS:

MR fingerprinting; QUEST; quantitative imaging; relaxation time; specific absorption rate

PMID:
26924639
PMCID:
PMC5002389
DOI:
10.1002/mrm.26173
[Indexed for MEDLINE]
Free PMC Article

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