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Trends Genet. 1989 Oct;5(10):342-7.

Fine-tuning of MHC class II gene expression in defined microenvironments.

Abstract

Strict control of major histocompatibility complex class II gene expression is essential for proper functioning of the immune system. Recent transgenic mouse studies have revealed an intricate fine-tuning of class II gene transcription in microenvironments such as the germinal centers and thymic cortex and medulla.

PMID:
2692242
DOI:
10.1016/0168-9525(89)90140-6
[Indexed for MEDLINE]

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