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Transplant Proc. 2016 Jan-Feb;48(1):92-5. doi: 10.1016/j.transproceed.2016.01.006.

Seroprevalence of Helicobacter pylori Infection in Renal Transplant Recipient Attending Duhok Kidney Disease Center.

Author information

1
Department of Internal Medicine, College of Medicine, University of Duhok, Duhok, Iraq. Electronic address: nawfal.hussein@yahoo.com.
2
Department of Internal Medicine, College of Medicine, University of Duhok, Duhok, Iraq.
3
Department of Hematology, College of Pharmacy, University of Duhok, Duhok, Iraq.
4
Duhok Kidney Disease Center, Duhok, Iraq.
5
Infection Control Department, DOH, Duhok, Iraq.
6
Department of Surgery, College of Medicine, University of Duhok, Duhok, Iraq.
7
Department of Biology, Faculty of Sciences, University of Zakho, Zakho, Iraq.

Abstract

INTRODUCTION:

Helicobacter pylori plays an important role in the development of gastritis, peptic ulcer disease, and gastric cancer in the general population. Although dyspeptic complaints are frequent in renal transplant subjects, the role of H pylori in such complaints is not clear. This study was conducted to examine the prevalence of H pylori infection in patients with renal transplant and its role in the development of upper gastrointestinal tract (GIT) symptoms.

MATERIALS AND METHODS:

We compared the prevalence of H pylori in 109 renal transplant subjects with the prevalence of 161 healthy volunteers using an enzyme-linked immunosorbent assay to measure anti-H pylori IgG. Then, within the transplant group, we stratified our data in accordance with different variables, including upper GIT symptoms, sex, education level, smoking, and dialysis history.

RESULTS:

The prevalence of H pylori in the control group was 111 of 161 (68.9%), which was significantly higher than that found in renal transplant subjects (48/109; 43.04%; P = .001). Within the transplant group, no association was found between immunoglobulin G positivity and different variables including upper GIT symptoms, sex, education level, smoking, and dialysis history.

CONCLUSIONS:

The prevalence of H pylori was lower in transplant subjects than that of general population. Upper GIT symptoms were equally found in both groups. Hence, the routine eradication of H pylori might not be indicated.

[Indexed for MEDLINE]

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