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Mol Cell Endocrinol. 2016 Apr 15;425:26-36. doi: 10.1016/j.mce.2016.02.013. Epub 2016 Feb 18.

STAMPing at the crossroads of normal physiology and disease states.

Author information

1
Department of Biosciences, University of Oslo, Oslo, Norway.
2
Department of Biosciences, University of Oslo, Oslo, Norway; Institute for Cancer Genetics and Informatics, Oslo University Hospital, Oslo, Norway. Electronic address: fahris@ibv.uio.no.

Abstract

The six transmembrane protein of prostate (STAMP) proteins, also known as six transmembrane epithelial antigen of prostate (STEAPs), comprises three members: STAMP1-3. Their expression is regulated by a variety of stimuli, including hormones and cytokines, in varied settings and tissues with important roles in secretion and cell differentiation. In addition, they are implicated in metabolic and inflammatory diseases and cancer. Here, we review the current knowledge on the role of STAMPs in both physiological and pathological states.

KEYWORDS:

Inflammation; Ironreductase; Metabolism; Prostate cancer; STAMP; STEAP

PMID:
26911931
DOI:
10.1016/j.mce.2016.02.013
[Indexed for MEDLINE]

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