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Fetal Diagn Ther. 2016;40(3):174-180. Epub 2016 Feb 25.

Endoscopic Placental Laser Coagulation in Dichorionic and Monochorionic Triplet Pregnancies.

Author information

1
Harris Birthright Research Centre of Fetal Medicine, King's College Hospital, London, UK.

Abstract

OBJECTIVE:

To report the outcome of monochorionic (MC) and dichorionic (DC) triamniotic (TA) triplet pregnancies treated with endoscopic laser coagulation of the communicating placental vessels for severe feto-fetal transfusion syndrome (FFTS) and selective fetal growth restriction (sFGR).

METHODS:

Laser surgery was performed at 18 (15-24) weeks' gestation in 11 MCTA and 33 DCTA pregnancies complicated by FFTS and 14 DCTA pregnancies complicated by sFGR. Data from our study and previous reports were pooled using meta-analytic techniques.

RESULTS:

Survival of at least one baby and survival among all fetuses was 97.0 and 72.7% in DCTA pregnancies with FFTS, 78.6 and 52.4% in DCTA pregnancies with sFGR and 81.8 and 39.4% in MCTA pregnancies with FFTS. In the combined data from our study and previous reports, the pooled survival rates in 132 DCTA pregnancies with FFTS were 94.4 and 76.1%, and in 29 MCTA pregnancies with FFTS, they were 80.6 and 57.5%.

CONCLUSIONS:

Survival after laser surgery is higher in DC triplets with FFTS than in those with sFGR and in DC than in MC triplets with FFTS.

PMID:
26910557
DOI:
10.1159/000443792
[Indexed for MEDLINE]
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