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World J Gastroenterol. 2016 Feb 21;22(7):2304-13. doi: 10.3748/wjg.v22.i7.2304.

Chronic pancreatitis: A diagnostic dilemma.

Author information

1
Sinead N Duggan, Hazel M Ní Chonchubhair, Oladapo Lawal, Donal B O'Connor, Kevin C Conlon, Professorial Surgical Unit, Department of Surgery, Trinity College Dublin, Centre for Pancreatico-Biliary Diseases, Trinity Centre for Health Sciences, Tallaght Hospital, 24 Dublin, Ireland.

Abstract

Typical clinical symptoms of chronic pancreatitis are vague and non-specific and therefore diagnostic tests are required, none of which provide absolute diagnostic certainly, especially in the early stages of disease. Recently-published guidelines bring much needed structure to the diagnostic work-up of patients with suspected chronic pancreatitis. In addition, novel diagnostic modalities bring promise for the future. The assessment and diagnosis of pancreatic exocrine insufficiency remains challenging and this review contests the accepted perspective that steatorrhea only occurs with > 90% destruction of the gland.

KEYWORDS:

Diagnosis; Exocrine pancreatic insufficiency; Malabsorption; Pancreatic enzyme replacement therapy; Pancreatitis, chronic

PMID:
26900292
PMCID:
PMC4735004
DOI:
10.3748/wjg.v22.i7.2304
[Indexed for MEDLINE]
Free PMC Article

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