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Iran Biomed J. 2017 Jan;21(1):57-60. Epub 2016 Jul 5.

Seroepidemiology of HTLV-1 and HTLV-2 Infection in Neyshabur City, North-Eastern Iran, during 2010-2014.

Author information

1
Medical Diagnostic Laboratory of Neyshabour, Center of Medical, Pathological and Genetic Diagnostic Services, Iranian Academic Center for Education, Culture and Research (ACECR), Mashhad Branch, Mashhad, Iran.
2
Department of Microbiology, Islamic Azad University, Tehran Medical Science Branch, Tehran, Iran.
3
Department of Microbiology, Faculty of Medicine, AJA University of Medical Sciences, Tehran, Iran.
4
Department of Biology, Faculty of Sciences, University of Isfahan, Isfahan, Iran.
5
Shahrekord University of Medical Sciences, Shahrekord, Iran.

Abstract

BACKGROUND:

Retroviruses of human T-lymphotropic viruses (HTLV-1 and HTLV-2) have been demonstrated to be endemic in the north-eastern region of Iran. This study was aimed to determine the HTLV-1 and HTLV-2 prevalence among healthy individuals in Neyshabur City during 2010-2014.

METHODS:

A total of 8054 blood samples were collected from healthy participants in Neyshabur, North-Eastern Iran. The blood samples were screened for the presence of specific antibodies against HTLV-1 and HTLV-2 by using ELISA according to the manufacturer's instructions.

RESULTS:

The overall seropositivity rate for HTLV-1 and HTLV-2 was found to be 6.55% (528 out of 8054) among participants.

CONCLUSION:

Both HTLV-1 and HTLV-2 were demonstrated to be at a high rate in healthy individuals. However, a smaller number of asymptomatic carriers were found in this study, as compared to those identified in previous investigations in the city.

KEYWORDS:

Enzyme-linked immunosorbent assay; Human T-lymphotropic viruse; Iran; Seroepidemiology

PMID:
26899860
PMCID:
PMC5141255
[Indexed for MEDLINE]
Free PMC Article

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