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J Acupunct Meridian Stud. 2016 Feb;9(1):22-5. doi: 10.1016/j.jams.2015.11.035. Epub 2015 Nov 27.

Waiguan Stimulation May Kindle Anticorrelated Brain Networks: Functional Magnetic Resonance Imaging Data Revisited.

Author information

1
Department of Clinical Medicine, University of Bergen, Bergen, Norway; The First People's Hospital of Shunde, Shunde, China. Electronic address: gustav.wik@k1.uib.no.
2
Department of Acupuncture and Moxibustion, School of Traditional Chinese Medicine, Southern Medical University, Guangzhou, China.
3
Department of Acupuncture and Moxibustion, School of Traditional Chinese Medicine, Southern Medical University, Guangzhou, China; The First People's Hospital of Shunde, Shunde, China.
4
Department of Meridian Studies, School of Acupuncture and Massage, Guangzhou University of Traditional Chinese Medicine, Guangzhou, China. Electronic address: lai1023@163.com.
5
Department of Meridian Studies, School of Acupuncture and Massage, Guangzhou University of Traditional Chinese Medicine, Guangzhou, China.
6
Institute of High Energy Physics, Chinese Academy of Science, Beijing, China.

Abstract

Subtraction of functional magnetic resonance imaging activity data results in a loss of information regarding possible general patterns of brain activation under experimental conditions. We, hence, reanalyzed previous Waiguan acupuncture data to qualitatively elucidate patterns of cerebral correlations to acupuncture and placebo conditions. Healthy individuals (n=24) were randomly allocated to true and sham Waiguan acupuncture and to true and sham needling of a nonacupuncture point (nonacupoint), and functional magnetic resonance imaging scans were performed during stimulation. Statistical parametric mapping group comparisons revealed clearly different patterns of activation between Waiguan stimulation and the corresponding stimulation of a nonacupoint. The former condition produced less neocortical activation than the nonacupoint stimulation. Cerebellar activation was typically seen only during true Waiguan acupuncture. The reduced neocortical activity during both true and sham Waiguan acupuncture may indicate that this point activates anticorrelated networks, with possible intrinsic healing properties. Cerebellar activation during true Waiguan acupuncture implies the region's influence on healing networks.

KEYWORDS:

Waiguan; acupoint; brain imaging; cognition; default-mode network

PMID:
26896073
DOI:
10.1016/j.jams.2015.11.035
[Indexed for MEDLINE]
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