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Pol Merkur Lekarski. 2016 Jan;40(235):56-60.

[The use of stem cells in some rheumatic diseases].

[Article in Polish]

Author information

1
Central Clinical Hospital of the Ministry of Internal Affair and Administration in Warsaw, Poland: Observation Department.
2
Central Clinical Hospital of the Ministry of Internal Affair and Administration in Warsaw, Poland: Department of Plastic Surgery.
3
Central Clinical Hospital of the Ministry of Internal Affair and Administration in Warsaw, Poland: Department of Dermatology;
4
Chair and Department of Natural Anatomy, Medical University of Lublin, Poland.

Abstract

Stem cells (SC) are characterized by the possibility of a potentially unlimited number of divisions, that are, its self-renewal and differentiation pot in all tissues of the body. The term "stem cells" was first used by the Russian histologist Alexander Maksimova in 1908 in relation to the hematopoietic stem cell (HSC - haematopoietic stem cells). SC, because of their ability to self-renewal and proliferation enormous potential, became the subject of numerous research around the world. These studies offer hope for improving the prognosis and optimization methods for the treatment of many types of diseases, including diseases of the developing autoimmune which include rheumatic diseases. Pain associated with the most common rheumatic diseases, like rheumatoid arthritis and osteoarthritis, cause temporary restriction of efficiency, frequent use of sick leave and abuse of painkillers. Rheumatic diseases often have young people in the labor force, have a chronic condition, and despite of the treatment over time lead to permanent disability and even premature death. Therapy with stem cells, can become an effective alternative to standard therapies used so far. The results of the first studies on the use of stem cells are promising and warrant further work on their application not only in rheumatic diseases.

KEYWORDS:

osteoarthritis; rheumatoid arthritis; stem cells

PMID:
26891439
[Indexed for MEDLINE]

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