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Int Forum Allergy Rhinol. 2016 Feb;6 Suppl 1:S22-209. doi: 10.1002/alr.21695.

International Consensus Statement on Allergy and Rhinology: Rhinosinusitis.

Author information

1
University of Utah.
2
University of Colorado.
3
Stanford University.
4
Oregon Health Science University.
5
University of Chicago.
6
Rush University.
7
Universidad de Barcelona.
8
Harvard Medical School.
9
Vanderbilt University.
10
University of Arizona.
11
University of Texas Medical School at Houston.
12
University of Pennsylvania.
13
Emory University.
14
Université de Montréal.
15
Samsung Medical Center.
16
University of Auckland.
17
University of Pittsburgh.
18
University of Amsterdam.
19
University Hospital, Leiden, Netherlands-Hygeia Hospital, Athens, Greece.
20
University of California, San Francisco.
21
Dr. Horst Schmidt Kliniken.
22
Massachusetts General Hospital.
23
Eastern Virginia Medical School.
24
University of New South Wales and Macquarie University.
25
University Hospitals Leuven.
26
Guy's Hospital.
27
University of Lorraine.
28
University of British Columbia.
29
Northwestern University.
30
Georgia Regents University.
31
Medical University in Lodz.
32
Johns Hopkins University.
33
Sinus & Nasal Institute of Florida.
34
Foundation New York University.
35
Korea University.
36
Royal National Throat Nose and Ear Hospital, London, UK.
37
Private Practice.
38
University of Texas, Southwestern.
39
Uniformed Services University of Health Sciences.
40
Jikei University.
41
University of Washington.
42
University of Siena.
43
Washington University.
44
Medical College of Wisconsin.
45
University of Adelaide.
46
West Virginia University.
47
Medical University Innsbruck.
48
Pusan National University.
49
University of Calgary.
50
University of New South Wales.
51
Medical University of South Carolina.
52
University of North Carolina.
53
Cleveland Clinic Foundation.
54
Loyola University.
55
Weill Cornell Medical College.
56
Temple University.
57
Universidade de São Paulo.
58
National University of Singapore.
59
San Antonio Military Medical Center.
60
University of Alabama at Birmingham.
61
University of Alberta.
62
Capital Medical University.

Abstract

BACKGROUND:

The body of knowledge regarding rhinosinusitis(RS) continues to expand, with rapid growth in number of publications, yet substantial variability in the quality of those presentations. In an effort to both consolidate and critically appraise this information, rhinologic experts from around the world have produced the International Consensus Statement on Allergy and Rhinology: Rhinosinusitis (ICAR:RS).

METHODS:

Evidence-based reviews with recommendations(EBRRs) were developed for scores of topics, using previously reported methodology. Where existing evidence was insufficient for an EBRR, an evidence-based review (EBR)was produced. The sections were then synthesized and the entire manuscript was then reviewed by all authors for consensus.

RESULTS:

The resulting ICAR:RS document addresses multiple topics in RS, including acute RS (ARS), chronic RS (CRS)with and without nasal polyps (CRSwNP and CRSsNP), recurrent acute RS (RARS), acute exacerbation of CRS (AECRS), and pediatric RS.

CONCLUSION:

As a critical review of the RS literature, ICAR:RS provides a thorough review of pathophysiology and evidence-based recommendations for medical and surgical treatment. It also demonstrates the significant gaps in our understanding of the pathophysiology and optimal management of RS. Too often the foundation upon which these recommendations are based is comprised of lower level evidence. It is our hope that this summary of the evidence in RS will point out where additional research efforts may be directed.

KEYWORDS:

acute rhinosinusitis; chronic rhinosinusitis; endoscopic sinus surgery; evidence-based medicine; recurrent acute rhinosinusitis; rhinosinusitis; systematic review

PMID:
26889651
DOI:
10.1002/alr.21695
[Indexed for MEDLINE]

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