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Physiology (Bethesda). 2016 Mar;31(2):117-30. doi: 10.1152/physiol.00049.2015.

Obesity Impacts Fever and Sickness Behavior During Acute Systemic Inflammation.

Author information

1
Department of Veterinary-Physiology and Biochemistry, Justus-Liebig-University Giessen, Giessen, Germany; and Christoph.D.Rummel@vetmed.uni-giessen.de.
2
Department of Veterinary-Physiology and Biochemistry, Justus-Liebig-University Giessen, Giessen, Germany; and.
3
Brain Function Research Group, School of Physiology, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa.

Abstract

Obesity is reaching dramatic proportions in humans and is associated with a higher risk for cardiovascular disease, diabetes, and cognitive alterations, and a higher mortality during infection and inflammation. The focus of the present review is on the influence of obesity on the presentation of fever, sickness behavior, and inflammatory responses during acute systemic inflammation.

PMID:
26889017
DOI:
10.1152/physiol.00049.2015
[Indexed for MEDLINE]
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