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PLoS One. 2016 Feb 16;11(2):e0149015. doi: 10.1371/journal.pone.0149015. eCollection 2016.

Adverse Trends in Ischemic Heart Disease Mortality among Young New Yorkers, Particularly Young Black Women.

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Cardiovascular Clinical Research Center, NYU School of Medicine, New York, NY, United States of America.
New York City Department of Health and Mental Health, New York, NY, United States of America.
Department of Biostatistics, NYU School of Medicine, New York, NY, United States of America.
Department of Population Health, NYU School of Medicine, New York, NY, United States of America.



Ischemic heart disease (IHD) mortality has been on the decline in the United States for decades. However, declines in IHD mortality have been slower in certain groups, including young women and black individuals.


Trends in IHD vary by age, sex, and race in New York City (NYC). Young female minorities are a vulnerable group that may warrant renewed efforts to reduce IHD.


IHD mortality trends were assessed in NYC 1980-2008. NYC Vital Statistics data were obtained for analysis. Age-specific IHD mortality rates and confidence bounds were estimated. Trends in IHD mortality were compared by age and race/ethnicity using linear regression of log-transformed mortality rates. Rates and trends in IHD mortality rates were compared between subgroups defined by age, sex and race/ethnicity.


The decline in IHD mortality rates slowed in 1999 among individuals aged 35-54 years but not ≥55. IHD mortality rates were higher among young men than women age 35-54, but annual declines in IHD mortality were slower for women. Black women age 35-54 had higher IHD mortality rates and slower declines in IHD mortality than women of other race/ethnicity groups. IHD mortality trends were similar in black and white men age 35-54.


The decline in IHD mortality rates has slowed in recent years among younger, but not older, individuals in NYC. There was an association between sex and race/ethnicity on IHD mortality rates and trends. Young black women may benefit from targeted medical and public health interventions to reduce IHD mortality.

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