ST-segment abnormalities are associated with long-term prognosis in non-ST-segment elevation acute coronary syndromes: The ERICO-ECG study

J Electrocardiol. 2016 May-Jun;49(3):411-6. doi: 10.1016/j.jelectrocard.2016.01.005. Epub 2016 Jan 15.

Abstract

Introduction: We aimed to identify whether ST-segment abnormalities, in the admission or during in-hospital stay, are associated with survival and/or new incident myocardial infarction (MI) in 623 non-ST-elevation acute coronary syndrome participants of the Strategy of Registry of Acute Coronary Syndrome (ERICO) study.

Materials and methods: ERICO is conducted in a community-based hospital. ST-segment analysis was based on the Minnesota Code. We built Cox regression models to study whether ECG was an independent predictor for clinical outcomes.

Results: Median follow-up was 3years. We found higher risk of death due to MI in individuals with ST-segment abnormalities in the final ECG (adjusted hazard ratio: 2.68; 95% confidence interval: 1.14-6.28). Individuals with ST-segment abnormalities in any tracing had a non-significant trend toward a higher risk of fatal or new non-fatal MI (p=0.088).

Conclusions: ST-segment abnormalities after the initial tracing added long-term prognostic information.

Keywords: Cohort; Coronary heart disease; Electrocardiography; Prognosis.

Publication types

  • Controlled Clinical Trial
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Acute Coronary Syndrome / diagnosis*
  • Acute Coronary Syndrome / mortality*
  • Acute Coronary Syndrome / therapy
  • Aged
  • Algorithms
  • Brazil / epidemiology
  • Cohort Studies
  • Comorbidity
  • Diagnosis, Computer-Assisted / methods
  • Electrocardiography / methods*
  • Electrocardiography / statistics & numerical data*
  • Female
  • Hospitalization / statistics & numerical data
  • Humans
  • Longitudinal Studies
  • Male
  • Middle Aged
  • Non-ST Elevated Myocardial Infarction / diagnosis*
  • Non-ST Elevated Myocardial Infarction / mortality*
  • Non-ST Elevated Myocardial Infarction / therapy
  • Prevalence
  • Prognosis
  • Proportional Hazards Models
  • Reproducibility of Results
  • Risk Assessment / methods
  • Sensitivity and Specificity
  • Survival Analysis