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Int J Gynaecol Obstet. 2016 May;133(2):217-20. doi: 10.1016/j.ijgo.2015.08.025. Epub 2016 Jan 6.

Progestin-based contraceptive on the same day as medical abortion.

Author information

1
Department of Obstetrics and Gynecology, University of Illinois, Chicago, USA. Electronic address: jeanna.park@gmail.com.
2
Department of Obstetrics and Gynecology, University of Illinois, Chicago, USA.
3
Department of Obstetrics and Gynecology, Lower Umfolozi District War Memorial Hospital, Empangeni, South Africa.
4
Department of Obstetrics and Gynecology, University of Illinois, Chicago, USA; Department of Obstetrics and Gynecology, Center for Research on Women and Gender, Chicago, USA.

Abstract

OBJECTIVE:

To determine the success rate of medical abortion when a progestin-based contraceptive-either an etonogestrel implant or depot medroxyprogesterone acetate (DMPA) injection-is given on the same day as mifepristone for medical abortion.

METHODS:

In a retrospective chart review, data were assessed for women aged 15-49years who underwent medical abortion (≤63days of pregnancy) at two hospitals in KwaZulu Natal, South Africa, between August 2013 and July 2014. The women were given oral mifepristone (200mg) and buccal misoprostol (800μg), and received an etonogestrel implant or DMPA injection on the same day as mifepristone. The primary outcome was the success rate of medical abortion. Comparative data were obtained through a PubMed search.

RESULTS:

A total of 89 women were included. Complete termination was achieved in 87 (98%, 95% confidence interval 95%-100%) women. This success rate is similar to that reported in a previous systematic review of the rate of medical abortion success without progestin contraceptive administration (94.8%).

CONCLUSIONS:

Administration of a progestin-based contraceptive such as an etonogestrel implant or DMPA injection on the same day as mifepristone for medical abortion did not alter the success rates.

KEYWORDS:

Depot medroxyprogesterone acetate; Etonogestrel; Medical abortion

PMID:
26868071
PMCID:
PMC4892361
DOI:
10.1016/j.ijgo.2015.08.025
[Indexed for MEDLINE]
Free PMC Article

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