Send to

Choose Destination
Schweiz Med Wochenschr. 1989 Sep 23;119(38):1285-9.

[Naf/nap-1, a new peptide which activates neutrophil leukocytes].

[Article in German]

Author information

Theodor-Kocher-Institut, Universit├Ąt Bern.


NAF/NAP-1 is a novel tissue-derived chemotactic peptide. It consists of 72 amino acids and has no sequence homology to known cytokines. NAF/NAP-1 is produced by a wide variety of cells after stimulation with interleukin-1, tumor necrosis factor or endotoxin, and has the properties of a local mediator of neutrophil recruitment into diseased tissues. There are indications that NAF/NAP-1 is important in the pathophysiology of inflammatory conditions such as psoriasis, idiopathic pulmonary fibrosis, asbestosis, adult respiratory distress syndrome and different forms of arthritis.

[Indexed for MEDLINE]

Supplemental Content

Loading ...
Support Center