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Anesth Analg. 2016 Apr;122(4):1108-11. doi: 10.1213/ANE.0000000000001176.

Ultrasound Assessment of the Prokinetic Effect of Erythromycin in Trauma Patients with a Full Stomach: A Case Series.

Author information

1
From the *University of Lyon, Claude Bernard Lyon 1 University, Inserm, U1032, LabTau, and Department of Anesthesia and Intensive Care, Femme Mère Enfant Hospital, Hospices Civils de Lyon, Lyon, France; †University of Lyon, Claude Bernard Lyon 1 University, and Department of Anesthesia and Intensive Care, Édouard Herriot Hospital, Hospices Civils de Lyon, Lyon, France; ‡University of Lyon, Claude Bernard Lyon 1 University, and Department of Anesthesia and Intensive Care, Femme Mère Enfant Hospital, Hospices Civils de Lyon, Lyon, France; §Department of Anesthesia, University College London Hospitals NHS Foundation Trust, London, United Kingdom; and ‖University of Lyon, Claude Bernard Lyon 1 University, Department of Intensive Care, Lyon Sud Hospital, Hospices Civils de Lyon, Lyon, France.

Abstract

In this preliminary prospective noninterventional study, we assessed the prokinetic effect of 3 mg•kg erythromycin in nonfasted emergency trauma patients. Ultrasonographic measurements of the antral area were performed 30 minutes and immediately before the erythromycin infusion and serially at 30, 60, and 90 minutes after the start of the infusion. Gastric emptying rates before and after erythromycin infusion, and at each 30-minute period after erythromycin infusion, were then calculated. We found that gastric emptying rates were increased after erythromycin infusion although gastric content and volume remained similar.

PMID:
26859878
DOI:
10.1213/ANE.0000000000001176
[Indexed for MEDLINE]

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