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Cancer Discov. 2016 Feb;6(2):122-4. doi: 10.1158/2159-8290.CD-15-1493.

Pruning Cancer's Evolutionary Tree with Lesion-Directed Therapy.

Author information

1
University College London Cancer Institute and The Francis Crick Institute, London, United Kingdom.
2
University College London Cancer Institute and The Francis Crick Institute, London, United Kingdom. charles.swanton@crick.ac.uk.

Abstract

Next-generation sequencing of spatially and temporally separated biopsies and circulating tumor DNA directs therapy in response to tumor evolution and acquired resistance in colorectal cancer.

PMID:
26851181
PMCID:
PMC4746740
DOI:
10.1158/2159-8290.CD-15-1493
[Indexed for MEDLINE]
Free PMC Article

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