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Yonsei Med J. 2016 Mar;57(2):449-54. doi: 10.3349/ymj.2016.57.2.449.

Validation of the Korean Version of the DN4 Diagnostic Questionnaire for Neuropathic Pain in Patients with Lumbar or Lumbar-Radicular Pain.

Author information

1
Spine Center, Department of Orthopaedic Surgery, Seoul National University College of Medicine, Seoul National University Bundang Hospital, Seongnam, Korea.
2
Department of Anesthesiology & Pain Medicine, Kangdong Sacred Heart Hospital, Hallym University College of Medicine, Seoul, Korea.
3
Inserm U987, Ambroise Pare Hospital, Boulogne-Billancourt and UVSQ University, Versailles, France.
4
Department of Orthopaedic Surgery, Seoul National University College of Medicine, Seoul National University Hospital, Seoul, Korea.
5
Department of Mechanical and Control Engineering, The Cyber University of Korea, Seoul, Korea.
6
Spine Center, Department of Orthopaedic Surgery, Seoul National University College of Medicine, Seoul National University Bundang Hospital, Seongnam, Korea. highcervical@gmail.com.

Abstract

PURPOSE:

To evaluate the diagnostic value of the Korean version of the Douleur Neuropathique 4 (DN4) questionnaire and to validate this questionnaire in terms of psychometric properties in patients with chronic pain due to degenerative spinal disease.

MATERIALS AND METHODS:

The Korean version of the DN4 questionnaire, which was translated and linguistically validated by the MAPI Research Group, was tested on 83 patients with lumbar or lumbar-radicular pain. Test-retest reliability was evaluated in a subsample of 40 patients who completed two assessments with an interval of 2 weeks. Nociceptive pain and neuropathic component pain were diagnosed in 40 and 43 patients, respectively.

RESULTS:

The Cronbach's α coefficient of internal consistency was 0.819, and the test-retest intraclass correlation coefficient (3, 1) (95% confidence interval) was 0.813 (0.776-0.847) (n=40). The area under the receiver-operator characteristics curve was 0.953 (p<0.001), with 95% confidence interval between 0.869 and 0.990. The Korean version of the DN4 questionnaire showed a sensitivity of 100% and 87.1%, and a specificity of 88.2% and 94.1% at the cutoff value of 3/10 and 4/10, respectively, for discriminating neuropathic component pain.

CONCLUSION:

The present study demonstrated the good discriminatory power of DN4 between nociceptive pain and neuropathic component pain in patients with lumbar or lumbar-radicular pain.

KEYWORDS:

Douleur Neuropathique 4 questionnaire; Korean language; Neuropathic pain; psychometric validation

PMID:
26847299
PMCID:
PMC4740539
DOI:
10.3349/ymj.2016.57.2.449
[Indexed for MEDLINE]
Free PMC Article

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