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Lupus. 2016 Apr;25(4):339-42. doi: 10.1177/0961203316629558. Epub 2016 Feb 3.

Postural Orthostatic Tachycardia Syndrome (POTS)--A novel member of the autoimmune family.

Author information

1
Zabludowicz Center for Autoimmune Diseases, Sheba Medical Center, Tel Hashomer, Israel Sackler Faculty of Medicine, Tel Aviv University, Israel.
2
Faculty of Medicine, University of British Columbia, Vancouver, BC, Canada.
3
Zabludowicz Center for Autoimmune Diseases, Sheba Medical Center, Tel Hashomer, Israel Sackler Faculty of Medicine, Tel Aviv University, Israel Shoenfel@post.tau.ac.il.

Abstract

Postural orthostatic tachycardia syndrome (POTS) is a heterogeneous disorder of the autonomic nervous system in which a change from the supine position to an upright position causes an abnormally large increase in heart rate or tachycardia (30 bpm within 10 min of standing or head-up tilt). This response is accompanied by a decrease in blood flow to the brain and hence a spectrum of symptoms associated with cerebral hypoperfusion. Many of these POTS-related symptoms are also observed in chronic anxiety and panic disorders, and therefore POTS is frequently under- and misdiagnosed.

KEYWORDS:

Postural orthostatic tachycardia syndrome (POTS); autoantibodies; autoimmunity; chronic fatigue syndrome (CFS); human papilloma virus (HPV); molecular mimicry

PMID:
26846691
DOI:
10.1177/0961203316629558
[Indexed for MEDLINE]

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