Format

Send to

Choose Destination
Hum Genomics. 2016 Feb 3;10:6. doi: 10.1186/s40246-016-0062-6.

A review of the new HGNC gene family resource.

Author information

1
European Bioinformatics Institute (EMBL-EBI), Wellcome Genome Campus, Hinxton, Cambridgeshire, CB10 1SD, UK. kris@ebi.ac.uk.
2
European Bioinformatics Institute (EMBL-EBI), Wellcome Genome Campus, Hinxton, Cambridgeshire, CB10 1SD, UK. rseal@ebi.ac.uk.
3
European Bioinformatics Institute (EMBL-EBI), Wellcome Genome Campus, Hinxton, Cambridgeshire, CB10 1SD, UK. stweedie@ebi.ac.uk.
4
European Bioinformatics Institute (EMBL-EBI), Wellcome Genome Campus, Hinxton, Cambridgeshire, CB10 1SD, UK. wrightmw@stanford.edu.
5
Department of Genetics, Stanford University, Palo Alto, CA, 94304, USA. wrightmw@stanford.edu.
6
European Bioinformatics Institute (EMBL-EBI), Wellcome Genome Campus, Hinxton, Cambridgeshire, CB10 1SD, UK. elspeth@ebi.ac.uk.

Abstract

The HUGO Gene Nomenclature Committee (HGNC) approves unique gene symbols and names for human loci. As well as naming genomic loci, we manually curate genes into family sets based on shared characteristics such as function, homology or phenotype. Each HGNC gene family has its own dedicated gene family report on our website, www.genenames.org . We have recently redesigned these reports to support the visualisation and browsing of complex relationships between families and to provide extra curated information such as family descriptions, protein domain graphics and gene family aliases. Here, we review how our gene families are curated and explain how to view, search and download the gene family data.

PMID:
26842383
PMCID:
PMC4739092
DOI:
10.1186/s40246-016-0062-6
[Indexed for MEDLINE]
Free PMC Article

Supplemental Content

Full text links

Icon for BioMed Central Icon for PubMed Central
Loading ...
Support Center