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Int Dent J. 2016 Jun;66(3):136-43. doi: 10.1111/idj.12214. Epub 2016 Feb 1.

Dental amalgam exposure can elevate urinary mercury concentrations in children.

Author information

1
Department of Dental Hygiene, Taegu Science University 47 Yeongsong-ro Buk-gu, Daegu, Korea.
2
Department of Dental Hygiene, College of Science & Technology, Kyungpook National University, Daegu, Korea.
3
Department of Hospital Management, Graduate School of Public Health, Yonsei University, Seodaemun-gu, Seoul, Korea.
4
Faculty of Health Science, Daegu Haany University 1 Haanydae-ro, Gyeongsan-si, Gyeongsangbuk-do, Korea.
5
Department of Preventive Medicine and Public Health College of Medicine, Yeungnam University 170 Hyunchung-ro, Nam-gu, Daegu, Korea.
6
Department of Epidemiology and Biostatistics, Arnold School of Public Health, University of South Carolina, Columbia, SC, USA.
7
Department of Preventive Dentistry, School of Dentistry, Kyungpook National University, Daegu, Korea.

Abstract

OBJECTIVES:

Owing to its cost-effectiveness and operative convenience, dental amalgam remains in use as a restorative material for tooth caries in children in many countries. The aim of this study was to evaluate the relationship between dental amalgam exposure and urinary mercury (U-Hg) concentrations in children.

METHODS:

In this longitudinal study, 463, 367 and 348 children, 8-11 years of age, were evaluated at baseline, and at the first and second follow-up visits, respectively. The interval between each survey was 6 months. For the oral examination and urine sample, the amalgam-filled tooth surface (TS), and U-Hg and creatinine concentrations of participants were determined, and the cumulative amalgam-filled TS and cumulative creatinine-adjusted U-Hg were calculated. To assess potential covariates, socio-demographic factors, oral health behaviour and dietary factors were surveyed by questionnaire. Data were analysed by the t-test, correlation analysis and mixed-model analysis. The statistical analyses were performed using SPSS 18.0.

RESULTS:

Children with more than one amalgam-filled TS exhibited significantly higher creatinine-adjusted U-Hg concentrations than those without, in all three survey periods (P < 0.001). The results for the current and cumulative amalgam-filled TS significantly correlated with those for the current and cumulative creatinine-adjusted U-Hg concentration, respectively, in all surveys (P < 0.001). In the repeated-measures mixed model analysis, current and cumulative amalgam-filled TS was significantly related to current and cumulative creatinine-adjusted U-Hg concentration, respectively (P < 0.001).

CONCLUSIONS:

Amalgam-filled TS was significantly correlated with U-Hg concentrations in children. Therefore, dental amalgam exposure can affect the systemic mercury concentration in children.

KEYWORDS:

Amalgam; children; dental practice

PMID:
26833490
DOI:
10.1111/idj.12214
[Indexed for MEDLINE]

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