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Nat Rev Nephrol. 2016 Mar;12(3):182-91. doi: 10.1038/nrneph.2015.219. Epub 2016 Feb 1.

Kidney disease in children: latest advances and remaining challenges.

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Department of Anatomy and Developmental Biology, and the Development and Stem Cells Program, Monash Biomedicine Discovery Institute, 19 Innovation Walk, Monash University, Melbourne, Victoria 3800, Australia.
Division of Nephrology and Hypertension, Cincinnati Children's Hospital Medical Center, 3333 Burnet Avenue, MLC 7022, Cincinnati, Ohio 45229, USA.
Department of Paediatric Nephrology, Hannover Medical School, Carl-Neuberg-Strasse 1, Hannover NDS30625, Germany.
Centre for Paediatrics and Adolescent Medicine, Heidelberg University Hospital, Im Neuenheimer Feld 430, Heidelberg BW69120, Germany.
Great Ormond Street Hospital for Children NHS Foundation Trust and University College London Institute of Child Health, Great Ormond Street, London WC1N 3JH, UK.
Children's Mercy Hospital, University of Missouri-Kansas City School of Medicine, 2401 Gillham Road, Kansas City, Missouri 64108, USA.


To mark World Kidney Day 2016, Nature Reviews Nephrology invited six leading researchers to highlight the key advances and challenges within their specialist field of paediatric nephrology. Here, advances and remaining challenges in the fields of prenatal patterning, acute kidney injury, renal transplantation, genetics, cardiovascular health, and growth and nutrition, are all discussed within the context of paediatric and neonatal patients with kidney disease. Our global panel of researchers describe areas in which further studies and clinical advances are needed, and suggest ways in which research in these areas should progress to optimize renal care and long-term outcomes for affected patients.

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