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J Cardiovasc Magn Reson. 2016 Feb 1;18:8. doi: 10.1186/s12968-016-0227-4.

UK Biobank's cardiovascular magnetic resonance protocol.

Author information

1
William Harvey Research Institute, NIHR Cardiovascular Biomedical Research Unit at Barts, Queen Mary University of London, Charterhouse Square, London, EC1M 6BQ, UK. s.e.petersen@qmul.ac.uk.
2
Division of Brain Sciences, Department of Medicine, Imperial College, London, UK. p.matthews@imperial.ac.uk.
3
Division of Cardiovascular Medicine, Radcliffe Department of Medicine, University of Oxford, Oxford, UK. Jane.francis@cardiov.ox.ac.uk.
4
Division of Cardiovascular Medicine, Radcliffe Department of Medicine, University of Oxford, Oxford, UK. Matthew.robson@cardiov.ox.ac.uk.
5
William Harvey Research Institute, NIHR Cardiovascular Biomedical Research Unit at Barts, Queen Mary University of London, Charterhouse Square, London, EC1M 6BQ, UK. f.zemrak@qmul.ac.uk.
6
William Harvey Research Institute, NIHR Cardiovascular Biomedical Research Unit at Barts, Queen Mary University of London, Charterhouse Square, London, EC1M 6BQ, UK. r.boubertakh@qmul.ac.uk.
7
Department of Anatomy and Medical Imaging, University of Auckland, Auckland, New Zealand. a.young@auckland.ac.nz.
8
UK Biobank, Spectrum Way, Adswood, Stockport, Cheshire, SK3 0SA, UK. Sarah.hudson@ukbiobank.ac.uk.
9
Siemens Healthcare, Frimley, Surrey, GU16 8QD, UK. peter.weale@siemens.com.
10
UK Biobank, Spectrum Way, Adswood, Stockport, Cheshire, SK3 0SA, UK. Steve.garratt@ukbiobank.ac.uk.
11
UK Biobank, Spectrum Way, Adswood, Stockport, Cheshire, SK3 0SA, UK. Rory.collins@ctsu.ox.ac.uk.
12
Division of Cardiovascular Medicine, Radcliffe Department of Medicine, University of Oxford, Oxford, UK. stefanp@fmrib.ox.ac.uk.
13
Division of Cardiovascular Medicine, Radcliffe Department of Medicine, University of Oxford, Oxford, UK. Stefan.neubauer@cardiov.ox.ac.uk.

Abstract

BACKGROUND:

UK Biobank's ambitious aim is to perform cardiovascular magnetic resonance (CMR) in 100,000 people previously recruited into this prospective cohort study of half a million 40-69 year-olds.

METHODS/DESIGN:

We describe the CMR protocol applied in UK Biobank's pilot phase, which will be extended into the main phase with three centres using the same equipment and protocols. The CMR protocol includes white blood CMR (sagittal anatomy, coronary and transverse anatomy), cine CMR (long axis cines, short axis cines of the ventricles, coronal LVOT cine), strain CMR (tagging), flow CMR (aortic valve flow) and parametric CMR (native T1 map).

DISCUSSION:

This report will serve as a reference to researchers intending to use the UK Biobank resource or to replicate the UK Biobank cardiovascular magnetic resonance protocol in different settings.

PMID:
26830817
PMCID:
PMC4736703
DOI:
10.1186/s12968-016-0227-4
[Indexed for MEDLINE]
Free PMC Article

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