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Bundesgesundheitsblatt Gesundheitsforschung Gesundheitsschutz. 2016 Mar;59(3):336-43. doi: 10.1007/s00103-015-2295-2.

[Centralized biobanks: a basis for medical research].

[Article in German]

Author information

1
Hannover Unified Biobank (HUB), Medizinische Hochschule Hannover (MHH), CRC Hannover, Feodor-Lynen-Str. 15, 30625, Hannover, Deutschland.
2
Institut für Pathologie, Charité - Universitätsmedizin Berlin, Berlin, Deutschland.
3
Hannover Unified Biobank (HUB), Medizinische Hochschule Hannover (MHH), CRC Hannover, Feodor-Lynen-Str. 15, 30625, Hannover, Deutschland. Illig.Thomas@mh-hannover.de.

Abstract

Biobanks are the basis for a substantial part of biomedical research. The development, establishment and operation of biobanks are connected to a broad range of aspects, mainly concerning the preparation, storage, usage and dissemination of samples and associated data, in addition to the social and public involvement of these processes. These complex requirements can often only be managed in large centralized biobanks. In recent years, centralized clinical biobanks have been established in several university clinics in Germany. Similar activities take place in other European countries and worldwide. This article highlights the requirements and main tasks of centralized clinical biobanks: high-quality pre-analytics and sample storage, the creation of professional IT structures, data protection, ethical issues, in addition to quality and project management.

KEYWORDS:

Centralized biobanks in clinical environment; High quality sample generation and storage; Professional IT management; Project management; Quality management

PMID:
26830106
DOI:
10.1007/s00103-015-2295-2
[Indexed for MEDLINE]

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