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Adv Med Sci. 2016 Mar;61(1):169-74. doi: 10.1016/j.advms.2015.12.003. Epub 2016 Jan 13.

Positive effects of egg-derived phospholipids in patients with metabolic syndrome.

Author information

1
Department of Internal Medicine, 4th Military Hospital, Wroclaw, Poland; Division of Angiology, Wroclaw Medical University, Wroclaw, Poland. Electronic address: cathcor@poczta.onet.pl.
2
Department of Internal Medicine, 4th Military Hospital, Wroclaw, Poland.
3
Department of Animal Products Technology and Quality Management, Wroclaw University of Environmental and Life Sciences, Wroclaw, Poland.
4
Department of Internal Medicine, 4th Military Hospital, Wroclaw, Poland; Division of Angiology, Wroclaw Medical University, Wroclaw, Poland.

Abstract

PURPOSE:

Patients with metabolic syndrome (MBS) have an increased risk of all-cause mortality, especially from cardiovascular disease. Egg phospholipids (PL) have been shown to exert a positive impact on cholesterol metabolism and inflammation; eggs are an important source of PL. Our study examined potential effects of egg-yolk-derived PL in non-diabetic patients with MBS.

METHODS:

The study group consisted of 40 patients with MBS diagnosed according to IDF criteria and divided into an experimental group receiving the PL preparation (n-6: n-3 fatty acids ratio: 1.79) and the comparison group receiving an olive oil preparation, for one month (2012/2013year). The studied dosage was 45ml (15ml 3 times per day). It was a randomized, double blinded study.

RESULTS:

The waist to hip ratio, GGTP levels, plasma platelet concentrations and flow mediated vasodilation of brachial artery (FMD) significantly improved in the experimental group. A significant decrease in daytime ABPM blood pressure was noticed in both groups.

CONCLUSIONS:

A phospholipid-enriched diet caused a significant improvement of endothelial vasodilatory function and a significant decrease in waist to hip ratio. A significant decrease in daytime systolic blood pressure were observed in both the phospholipid-enriched and oil-olive group.

KEYWORDS:

Civilization diseases; Dietary pattern; Flow mediated dilatation; Nutrition; Olive oil

PMID:
26829066
DOI:
10.1016/j.advms.2015.12.003
[Indexed for MEDLINE]

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