This report represents our initial experience with a new type of needle guide for amniocentesis, transabdominal chorionic villus biopsies, and funipuncture developed at the Ohio State University and tested at the Harris Birthright Centre for Fetal Medicine. This articulated needle guide is designed to combine the advantages of the existing needle guides and the freehand technique. The needle guide offers improved maneuverability compared with standard needle guides and maintains easy visualization of the needle.