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Haematologica. 2016 Feb;101(2):115-208. doi: 10.3324/haematol.2015.136739. Epub 2016 Jan 27.

The European Hematology Association Roadmap for European Hematology Research: a consensus document.

Collaborators (284)

Engert A, Balduini C, Brand A, Coiffier B, Cordonnier C, Döhner H, de Wit TD, Eichinger S, Fibbe W, Green T, de Haas F, Iolascon A, Jaffredo T, Rodeghiero F, Salles G, Schuringa JJ, André M, Andre-Schmutz I, Bacigalupo A, Bochud PY, Boer Md, Bonini C, Camaschella C, Cant A, Cappellini MD, Cazzola M, Celso CL, Dimopoulos M, Douay L, Dzierzak E, Einsele H, Ferreri A, De Franceschi L, Gaulard P, Gottgens B, Greinacher A, Greinacher A, Gresele P, Gribben J, de Haan G, Hansen JB, Hochhaus A, Kadir R, Kaveri S, Kouskoff V, Kühne T, Kyrle P, Ljungman P, Maschmeyer G, Méndez-Ferrer S, Milsom M, Mummery C, Ossenkoppele G, Pecci A, Peyvandi F, Philipsen S, Reitsma P, Ribera JM, Risitano A, Rivella S, Ruf W, Schroeder T, Scully M, Socie G, Staal F, Stanworth S, Stauder R, Stilgenbauer S, Tamary H, Theilgaard-Mönch K, Thein SL, Tilly H, Trneny M, Vainchenker W, Vannucchi AM, Viscoli C, Vrielink H, Zaaijer H, Zanella A, Zolla L, Zwaginga JJ, Martinez PA, van den Akker E, Allard S, Anagnou N, Andolfo I, Andrau JC, Angelucci E, Anstee D, Aurer I, Avet-Loiseau H, Aydinok Y, Bakchoul T, Balduini A, Balduini C, Barcellini W, Baruch D, Baruchel A, Bayry J, Bento C, van den Berg A, Bernardi R, Bianchi P, Bigas A, Biondi A, Bohonek M, Bonnet D, Borchmann P, Borregaard N, Brækkan S, van den Brink M, Brodin E, Bullinger L, Buske C, Butzeck B, Cammenga J, Campo E, Carbone A, Cervantes F, Cesaro S, Charbord P, Claas F, Cohen H, Conard J, Coppo P, Corrons JL, Costa Ld, Davi F, Delwel R, Dianzani I, Domanović D, Donnelly P, Drnovšek TD, Dreyling M, Du MQ, Dufour C, Durand C, Efremov D, Eleftheriou A, Elion J, Emonts M, Engelhardt M, Ezine S, Falkenburg F, Favier R, Federico M, Fenaux P, Fitzgibbon J, Flygare J, Foà R, Forrester L, Galacteros F, Garagiola I, Gardiner C, Garraud O, van Geet C, Geiger H, Geissler J, Germing U, Ghevaert C, Girelli D, Godeau B, Gökbuget N, Goldschmidt H, Goodeve A, Graf T, Graziadei G, Griesshammer M, Gruel Y, Guilhot F, von Gunten S, Gyssens I, Halter J, Harrison C, Harteveld C, Hellström-Lindberg E, Hermine O, Higgs D, Hillmen P, Hirsch H, Hoskin P, Huls G, Inati A, Johnson P, Kattamis A, Kiefel V, Kleanthous M, Klump H, Krause D, Hovinga JK, Lacaud G, Lacroix-Desmazes S, Landman-Parker J, LeGouill S, Lenz G, von Lilienfeld-Toal M, von Lindern M, Lopez-Guillermo A, Lopriore E, Lozano M, MacIntyre E, Makris M, Makris M, Mannhalter C, Martens J, Mathas S, Matzdorff A, Medvinsky A, Menendez P, Migliaccio AR, Miharada K, Mikulska M, Minard V, Montalbán C, de Montalembert M, Montserrat E, Morange PE, Mountford J, Muckenthaler M, Müller-Tidow C, Mumford A, Nadel B, Navarro JT, El Nemer W, Noizat-Pirenne F, O'Mahony B, Oldenburg J, Olsson M, Oostendorp R, Palumbo A, Passamonti F, Patient R, Peffault R, Pflumio F, Pierelli L, Piga A, Pollard D, Raaijmakers M, Radford J, Rambach R, Rao AK, Raslova H, Rebulla P, Rees D, Ribrag V, Rijneveld A, Rinalducci S, Robak T, Roberts I, Rodrigues C, Rosendaal F, Rosenwald A, Rule S, Russo R, Saglio G, Sanchez M, Scharf RE, Schlenke P, Semple J, Sierra J, So-Osman C, Soria JM, Stamatopoulos K, Stegmayr B, Stunnenberg H, Swinkels D, Barata JP, Taghon T, Taher A, Terpos E, Thachil J, Tissot JD, Touw I, Toye A, Trappe R, Traverse-Glehen A, Unal S, Vaulont S, Viprakasit V, Vitolo U, van Wijk R, Wójtowicz A, Zeerleder S, Zieger B.

Author information

1
Universität zu Köln, Cologne, Germany a.engert@uni-koeln.de.
2
IRCCS Policlinico San Matteo Foundation, Pavia, Italy.
3
Leids Universitair Medisch Centrum, Leiden, the Netherlands.
4
Université Claude Bernard, Lyon, France.
5
Hôpitaux Universitaires Henri Mondor, Créteil, France.
6
Universitätsklinikum Ulm, Germany.
7
European Hematology Association, The Hague, the Netherlands.
8
Medizinische Universität Wien, Vienna, Austria.
9
Cambridge Institute for Medical Research, United Kingdom.
10
Università Federico II di Napoli, Italy.
11
Université Pierre et Marie Curie, Paris, France.
12
Ospedale San Bortolo, Vicenza, Italy.
13
Hospices Civils de Lyon/Université de Lyon, Pierre-Bénite, France.
14
Universitair Medisch Centrum Groningen, the Netherlands.

Abstract

The European Hematology Association (EHA) Roadmap for European Hematology Research highlights major achievements in diagnosis and treatment of blood disorders and identifies the greatest unmet clinical and scientific needs in those areas to enable better funded, more focused European hematology research. Initiated by the EHA, around 300 experts contributed to the consensus document, which will help European policy makers, research funders, research organizations, researchers, and patient groups make better informed decisions on hematology research. It also aims to raise public awareness of the burden of blood disorders on European society, which purely in economic terms is estimated at €23 billion per year, a level of cost that is not matched in current European hematology research funding. In recent decades, hematology research has improved our fundamental understanding of the biology of blood disorders, and has improved diagnostics and treatments, sometimes in revolutionary ways. This progress highlights the potential of focused basic research programs such as this EHA Roadmap.The EHA Roadmap identifies nine 'sections' in hematology: normal hematopoiesis, malignant lymphoid and myeloid diseases, anemias and related diseases, platelet disorders, blood coagulation and hemostatic disorders, transfusion medicine, infections in hematology, and hematopoietic stem cell transplantation. These sections span 60 smaller groups of diseases or disorders.The EHA Roadmap identifies priorities and needs across the field of hematology, including those to develop targeted therapies based on genomic profiling and chemical biology, to eradicate minimal residual malignant disease, and to develop cellular immunotherapies, combination treatments, gene therapies, hematopoietic stem cell treatments, and treatments that are better tolerated by elderly patients.

PMID:
26819058
PMCID:
PMC4938336
DOI:
10.3324/haematol.2015.136739
[Indexed for MEDLINE]
Free PMC Article

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