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Haematologica. 2016 Apr;101(4):e135-8. doi: 10.3324/haematol.2015.136051. Epub 2016 Jan 27.

Clinical impact of small subclones harboring NOTCH1, SF3B1 or BIRC3 mutations in chronic lymphocytic leukemia.

Author information

1
Division of Hematology, Department of Translational Medicine, Amedeo Avogadro University of Eastern Piedmont, Novara, Italy.
2
Center for Topology of Cancer Evolution and Heterogeneity, Department of Biomedical Informatics and Center for Computational Biology and Bioinformatics, Columbia University, New York, NY, USA.
3
Clinical and Experimental Onco-Hematology, Centro di Riferimento Oncologico, Aviano, Italy.
4
Hematology, Department of Cellular Biotechnologies and Hematology, Sapienza University, Rome, Italy.
5
Division of Hematology, Department of Translational Medicine, Amedeo Avogadro University of Eastern Piedmont, Novara, Italy rossidav@med.unipmn.it.

KEYWORDS:

BIRC3; NOTCH1; SF3B1; TP53; chronic lymphocytic leukemia; evolution; frequency; prognostic impact; subclones

PMID:
26819056
PMCID:
PMC5004398
DOI:
10.3324/haematol.2015.136051
[Indexed for MEDLINE]
Free PMC Article

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